预测戒烟效果持续性的前瞻性研究：一项随机对照临床试验结果
2010/02/01
寻找可用于指导戒烟及改善戒烟效果的戒烟前相关变量的过程成败参半。该过程的关键第一步是寻找能可靠预测戒烟效果的变量。近期一些研究（主要是回顾性研究）关于持续戒烟与吸烟效果检测指标间的相关性结果并不一致。本试验采用一项随机临床试验(N=241) 的数据，前瞻性研究戒烟持续性对戒烟效果的预测能力。多变量分析并不支持我们的假设：戒烟持续性不能预测戒烟效果。我们将本次研究与前期研究的结果进行了对比，重点讨论了与戒烟持续性有关的理论和检测问题。
我们的结论为将来的研究指出了方向，包括对戒烟持续性和理论相关架构的关系进行概念性澄清，以及对可能缓和理论架构和戒烟效果直接关系的变量进行研究。
（陈欣 审校）
Addict Behav. 2010 Feb;35(2):179-82. Epub 2009 Sep 22.
A prospective study of persistence in the prediction of smoking cessation outcome: results from a randomized clinical trial.
Kalman D, Hoskinson R, Sambamoorthi U, Garvey AJ.
Harvard School of Dental Medicine, 188 Longwood Avenue, Boston, MA 02115, USA.
Research has had mixed success in identifying pretreatment variables which can be used to guide treatment and enhance outcome. A critical first step in the process is to identify variables that reliably predict outcome. Some recent studies, largely retrospective, have found mixed evidence on the relationship between task persistence and smoking outcome measures. In the present study, we use data from a randomized clinical trial (N=241) to prospectively investigate the ability of persistence to predict outcome. Findings from multivariate analyses did not support our hypotheses: persistence did not predict outcome. We discuss these findings in relation to previous studies by focusing on theoretical and measurement issues related to the study of persistence in smoking cessation research. We conclude by recommending directions for future research, including conceptual clarification of the relationship between persistence and theoretically related constructs and investigations of variables that may moderate relationships between these constructs and cessation outcome.
Addict Behav. 2010 Feb;35(2):179-82. Epub 2009 Sep 22.
我们的结论为将来的研究指出了方向，包括对戒烟持续性和理论相关架构的关系进行概念性澄清，以及对可能缓和理论架构和戒烟效果直接关系的变量进行研究。
（陈欣 审校）
Addict Behav. 2010 Feb;35(2):179-82. Epub 2009 Sep 22.
A prospective study of persistence in the prediction of smoking cessation outcome: results from a randomized clinical trial.
Kalman D, Hoskinson R, Sambamoorthi U, Garvey AJ.
Harvard School of Dental Medicine, 188 Longwood Avenue, Boston, MA 02115, USA.
Research has had mixed success in identifying pretreatment variables which can be used to guide treatment and enhance outcome. A critical first step in the process is to identify variables that reliably predict outcome. Some recent studies, largely retrospective, have found mixed evidence on the relationship between task persistence and smoking outcome measures. In the present study, we use data from a randomized clinical trial (N=241) to prospectively investigate the ability of persistence to predict outcome. Findings from multivariate analyses did not support our hypotheses: persistence did not predict outcome. We discuss these findings in relation to previous studies by focusing on theoretical and measurement issues related to the study of persistence in smoking cessation research. We conclude by recommending directions for future research, including conceptual clarification of the relationship between persistence and theoretically related constructs and investigations of variables that may moderate relationships between these constructs and cessation outcome.
Addict Behav. 2010 Feb;35(2):179-82. Epub 2009 Sep 22.
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戒烟公共卫生临床示范项目在患有创伤后应激障碍的退伍军人中的应用
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药物治疗以获得短期戒烟的有效性：系统综述和荟萃分析
