在有或无高强度吸烟史的轻度吸烟者中比较戒烟计划的作用
2009/05/18
本项试验研究了咨询强度（高或低）与安非他酮或尼古丁贴剂对戒烟的作用。共260名研究对象（每天吸烟（cpd）6～15支）参与本项为期1年的试验，旨在研究戒烟治疗的有效性。4组吸烟者采用盲法给药，在3个不同的随访期内（治疗后12，26和52周）比较治疗的完成情况和戒烟情况。2个咨询组具有相似的治疗完成率（根据咨询的出席情况和用药的坚持情况）。
结果表明，治疗对戒断和持续戒断具有一定作用，早期随访（第12周）显示，戒断需较高的咨询强度。有高强度吸烟（≥20 cpd）史的研究对象和非裔美国吸烟者在研究结束时出现戒烟的可能性较小。本研究在鉴别吸烟较少者的治疗需求上具有一定作用。
（刘国梁 摘译）
（Gariti P,etal.J Subst Abuse Treat. 2009 Mar 30. [Epub ahead of print]）
Gariti P, et al. J Subst Abuse Treat. 2009 Mar 30. [Epub ahead of print]
Comparing smoking treatment programs for lighter smokers with and without a history of heavier smoking.
The study examined the impact of counseling intensity (high vs. low) combined with either bupropion or the nicotine patch. Two hundred sixty participants smoking 6 to 15 cigarettes per day (cpd) were enrolled in a yearlong study to examine the effects of treatment. Four groups of smokers under medication-blinded conditions were compared for treatment completion and abstinence at three follow-up points from the initiation of treatment (Weeks 12, 26, and 52). Both counseling groups had similar treatment completion rates (i.e., defined by a combination of counseling attendance and medication adherence levels). There was a main treatment effect for abstinence favoring the high counseling condition in early follow-up (Week 12) and for continuous abstinence. Participants with a history of heavier smoking (>/=20 cpd) and African American smokers were least likely to be smoke free at the end of the study. The study has implications for identifying the treatment needs of lighter smokers.
结果表明，治疗对戒断和持续戒断具有一定作用，早期随访（第12周）显示，戒断需较高的咨询强度。有高强度吸烟（≥20 cpd）史的研究对象和非裔美国吸烟者在研究结束时出现戒烟的可能性较小。本研究在鉴别吸烟较少者的治疗需求上具有一定作用。
（刘国梁 摘译）
（Gariti P,etal.J Subst Abuse Treat. 2009 Mar 30. [Epub ahead of print]）
Gariti P, et al. J Subst Abuse Treat. 2009 Mar 30. [Epub ahead of print]
Comparing smoking treatment programs for lighter smokers with and without a history of heavier smoking.
The study examined the impact of counseling intensity (high vs. low) combined with either bupropion or the nicotine patch. Two hundred sixty participants smoking 6 to 15 cigarettes per day (cpd) were enrolled in a yearlong study to examine the effects of treatment. Four groups of smokers under medication-blinded conditions were compared for treatment completion and abstinence at three follow-up points from the initiation of treatment (Weeks 12, 26, and 52). Both counseling groups had similar treatment completion rates (i.e., defined by a combination of counseling attendance and medication adherence levels). There was a main treatment effect for abstinence favoring the high counseling condition in early follow-up (Week 12) and for continuous abstinence. Participants with a history of heavier smoking (>/=20 cpd) and African American smokers were least likely to be smoke free at the end of the study. The study has implications for identifying the treatment needs of lighter smokers.
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在住院的年轻精神病患者中戒烟动机访谈对精神活性药物使用情况的影响
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禁止吸烟和吸烟的处理：澳大利亚精神科住院病房的政策和措施
