哮喘联盟

    目的与研究设计：采用平行分组的方法，对门诊患者在常规康复训练过程中进行戒烟的有效性研究。
    患者与方法：研究对象包括：干预组为康复训练中心顺续就诊的吸烟者同时进行戒烟治疗的102名患者，对照组为肺科医院戒烟中心顺续就诊的101名吸烟患者。对所有参与者进行体格检查、肺功能检查，以及相同的行为和/或药理学治疗。此外，干预组进行每周3次，持续3个月的康复训练。
    结果：通过检测呼出气中一氧化碳浓度(小于等于百万分之10)和家访来确定持续戒烟率。结果显示，干预组12个月后的持续戒烟率为68％，而对照组为32％。多变量分析显示，在校正了吸烟年限、吸烟数量、性别和治疗等因素后，康复训练与戒烟呈显著相关(优势比＝4.34, P<0.001)。
    结论：本研究显示，在常规康复训练过程中进行戒烟能够更高有效的帮助患者戒烟，强烈推荐将康复训练作为戒烟的一项内容。

（苏楠 审校）
Paone G, et al. J Rehabil Med. 2008 Aug;40(8):672-677.

The combination of a smoking cessation programme with rehabilitation increases stop-smoking rate.

Paone G, Serpilli M, Girardi E, Conti V, Principe R, Puglisi G, De Marchis L, Schmid G.

Department of Cardiovascular and Respiratory Sciences, University of Rome "La Sapienza", S. Camillo-Forlanini Hospital, Rome, Italy. rpaone1023@yahoo.com

OBJECTIVE AND STUDY DESIGN: A parallel group study to investigate the effectiveness of a smoking cessation programme performed during routine rehabilitation practice for outpatients. 
PATIENTS AND METHODS: The study participants comprised an intervention group of 102 consecutive smokers who underwent a smoking cessation programme in a rehabilitation centre and a control group of 101 consecutive smokers who were referred to a smoking cessation centre in a pulmonary hospital. All participants underwent physical examination,pulmonary function tests and received identical behavioural and/or pharmacological treatment. In addition, the intervention group underwent rehabilitation practice 3 times a week for 3 months. 
RESULTS: The continuous abstinence rate at 12 months, which was validated by an expired air carbon monoxide concentration of 10 parts per million or less and a household interview, was 68% in the intervention group and 32% in the control group. Multivariable analysis showed that rehabilitation was significantly associated with smoking cessation after adjusting for years of smoking, number of cigarettes smoked,gender and treatment (odds ratio = 4.34, p < 0.001). 
CONCLUSION: This study suggests that smoking cessation programmes during routine rehabilitation may be highly effective in helping smoking withdrawal and should be a strongly recommended component of rehabilitation practice.