确定持续性哮喘和COPD的最佳药物依从性

2021/08/24

   摘要
   坚持应用慢性呼吸道疾病的处方药物被认为是成功治疗的关键。然而,关于如何衡量依从性、什么是最佳依从性或什么是适当用药的目标,几乎没有明确共识。在研究患者或人群水平的药物利用率时,这些标准可能会有所不同。在慢性呼吸道疾病中持续用药的作用与更好的预后相关。共享决策是一种实现适当程度的依从性的策略,这需要患者和提供者之间的协商和妥协。它还认识到,实现遵守目标的成功与否是共同的。因此,我们讨论了目前对呼吸道疾病患者依从性测量的认识,并确定了若要用更细致的方法来评估依从性还需要什么,从而获得可接受的患者预后。

 
(中日友好医院呼吸与危重症医学科 顾宪民 摘译 林江涛 审校)
(J Allergy Clin Immunol Pract. 2021 Aug 2;S2213-2198(21)00838-2. doi: 10.1016/j.jaip.2021.07.034.)

 
 
 
Defining optimal medication adherence for persistent asthma and COPD
 
David A Stempel, Leanne Kaye, Bruce G Bender
 
Abstract
Adherence to prescribed medications for chronic respiratory disease is considered a keystone for successful management. There is little consensus though, on how to measure adherence, what is optimal adherence or the goals of appropriate medication utilization. These criteria may differ when studying medication utilization at the patient or population level. The role of consistent medication use in chronic respiratory disease is associated with better outcomes. Shared decision-making is one strategy to achieve appropriate levels of adherence that requires negotiation, compromise by both patient and provider. It also recognizes that both success and failure to achieve goals of adherence is shared. As such, we discuss the current understanding of adherence measures in respiratory disease and identify the need for more nuanced approaches to evaluate adherence to reach acceptable patient outcomes.




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