信号素3A是一种很有前景的支气管哮喘治疗工具
2020/02/11
摘要
多年来，免疫介导性疾病和/或自身免疫性疾病的治疗专注于提高促炎过程的抑制。辅助性T细胞1（Th1）的产物，例如TNF-α，是第一个靶点。根据这种方法，抗IL-17也被添加到了这种旨在治疗牛皮癣和牛皮癣关节炎的抑制性抗炎疗法中。
Semaphorin3A is a promising therapeutic tool for bronchial asthma.
Toubi E et al. Allergy. 2019 Aug 23.
Abstract
For many years treatment for immune-mediated and or autoimmune diseases focused on improving suppression of pro-inflammatory processes. Products of T-helper 1 (Th1) cells such as TNF-α were the first to be targeted. In accordance with this approach, anti-IL-17 was also added to this arsenal of suppressive anti-inflammatory therapies intended to treat psoriasis and psoriatic arthritis.
多年来，免疫介导性疾病和/或自身免疫性疾病的治疗专注于提高促炎过程的抑制。辅助性T细胞1（Th1）的产物，例如TNF-α，是第一个靶点。根据这种方法，抗IL-17也被添加到了这种旨在治疗牛皮癣和牛皮癣关节炎的抑制性抗炎疗法中。
（中国医科大学附属第一医院 李文扬 摘译 杨冬 审校）
（Toubi E et al. Allergy. 2019 Aug 23.）
（Toubi E et al. Allergy. 2019 Aug 23.）
Semaphorin3A is a promising therapeutic tool for bronchial asthma.
Toubi E et al. Allergy. 2019 Aug 23.
Abstract
For many years treatment for immune-mediated and or autoimmune diseases focused on improving suppression of pro-inflammatory processes. Products of T-helper 1 (Th1) cells such as TNF-α were the first to be targeted. In accordance with this approach, anti-IL-17 was also added to this arsenal of suppressive anti-inflammatory therapies intended to treat psoriasis and psoriatic arthritis.
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生物学与疗法的交叉点：成人哮喘的2型靶向疗法
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重症哮喘患者长期阿奇霉素治疗可减少流感嗜血杆菌感染，增加了抗生素耐药性
