哮喘控制，肺功能，营养状况和与健康相关的生活质量：成年男性和女性哮喘之间的差异
2018/07/09
摘要
目标：为了评估巴西南部转诊中心接受治疗的哮喘患者的健康相关生活质量，确定男性和女性患者之间的差异，以及评估男性和女性在哮喘控制，肺功能和营养方面的差异状态。
方法：此试验为一项横断面研究，参与者包括在哮喘门诊就诊的≥18岁的患者。我们评估了临床参数，肺功能，营养状况和生活质量。
结果：共有198名患者参与了该研究。 平均年龄为56.2±14.8岁，81.8％为女性。 难控制哮喘患者的比例在女性中高于男性（63.0％对44.4％; p = 0.041）。 女性的体重指数（BMI）和体脂百分比高于男性（30.2±5.8 kg / m2 vs. 26.9±4.5 kg / m2和37.4±6.4％vs。26.5±7.4％; p = 0.002和 p <0.001）。 在以下领域，女性的生活质量低于男性：症状（3.8±1.5比4.6±1.7; p = 0.006）; 活动受限（3.6±1.3对4.4±1.5; p = 0.001）; 情绪（3.6±1.9 vs. 4.5±1.7; p = 0.014）; 和环境刺激（3.2±1.6对4.3±1.9; p = 0.001）。
结论：在与健康相关的生活质量，哮喘控制，BMI，体脂百分比及合并症方面，男性哮喘患者似乎比女性哮喘患者要控制得好。
Asthma control, lung function, nutritional status, and health-related quality of life: differences between adult males and females with asthma
Forte GC, Hennemann ML, Dalcin PTR.
ABSTRACT
Objective: To evaluate health-related quality of life in asthma patients treated at a referral center in southern Brazil, identifying differences between male and female patients, as well as to evaluate differences between the males and females in terms of asthma control, lung function, and nutritional status.
Methods: This was a cross-sectional study involving patients ≥ 18 years of age treated at an asthma outpatient clinic. We evaluated clinical parameters, lung function, nutritional status, and quality of life.
Results: A total of 198 patients completed the study. The mean age was 56.2 ± 14.8 years, and 81.8% were female. The proportion of patients with uncontrolled asthma was higher among females than among males (63.0% vs. 44.4%; p = 0.041). The body mass index (BMI) and percentage of body fat were higher in females than in males (30.2 ± 5.8 kg/m2 vs. 26.9 ± 4.5 kg/m2 and 37.4 ± 6.4% vs. 26.5 ± 7.4%; p = 0.002 and p < 0.001, respectively). Quality of life was lower in females than in males in the following domains: symptoms (3.8 ± 1.5 vs. 4.6 ± 1.7; p = 0.006); activity limitation (3.6 ± 1.3 vs. 4.4 ± 1.5; p = 0.001); emotional function (3.6 ± 1.9 vs. 4.5 ± 1.7; p = 0.014); and environmental stimuli (3.2 ± 1.6 vs. 4.3 ± 1.9; p = 0.001).
Conclusions:Male asthma patients appear to fare better than do female asthma patients in terms of health-related quality of life, asthma control, BMI, percentage of body fat, and comorbidities.
目标：为了评估巴西南部转诊中心接受治疗的哮喘患者的健康相关生活质量，确定男性和女性患者之间的差异，以及评估男性和女性在哮喘控制，肺功能和营养方面的差异状态。
方法：此试验为一项横断面研究，参与者包括在哮喘门诊就诊的≥18岁的患者。我们评估了临床参数，肺功能，营养状况和生活质量。
结果：共有198名患者参与了该研究。 平均年龄为56.2±14.8岁，81.8％为女性。 难控制哮喘患者的比例在女性中高于男性（63.0％对44.4％; p = 0.041）。 女性的体重指数（BMI）和体脂百分比高于男性（30.2±5.8 kg / m2 vs. 26.9±4.5 kg / m2和37.4±6.4％vs。26.5±7.4％; p = 0.002和 p <0.001）。 在以下领域，女性的生活质量低于男性：症状（3.8±1.5比4.6±1.7; p = 0.006）; 活动受限（3.6±1.3对4.4±1.5; p = 0.001）; 情绪（3.6±1.9 vs. 4.5±1.7; p = 0.014）; 和环境刺激（3.2±1.6对4.3±1.9; p = 0.001）。
结论：在与健康相关的生活质量，哮喘控制，BMI，体脂百分比及合并症方面，男性哮喘患者似乎比女性哮喘患者要控制得好。
（中日友好医院呼吸与危重症医学科 张 鑫 摘译 林江涛 审校）
（J Bras Pneumol. 2018 Jun 25. pii: S1806-37132018005002104.）
（J Bras Pneumol. 2018 Jun 25. pii: S1806-37132018005002104.）
Asthma control, lung function, nutritional status, and health-related quality of life: differences between adult males and females with asthma
Forte GC, Hennemann ML, Dalcin PTR.
ABSTRACT
Objective: To evaluate health-related quality of life in asthma patients treated at a referral center in southern Brazil, identifying differences between male and female patients, as well as to evaluate differences between the males and females in terms of asthma control, lung function, and nutritional status.
Methods: This was a cross-sectional study involving patients ≥ 18 years of age treated at an asthma outpatient clinic. We evaluated clinical parameters, lung function, nutritional status, and quality of life.
Results: A total of 198 patients completed the study. The mean age was 56.2 ± 14.8 years, and 81.8% were female. The proportion of patients with uncontrolled asthma was higher among females than among males (63.0% vs. 44.4%; p = 0.041). The body mass index (BMI) and percentage of body fat were higher in females than in males (30.2 ± 5.8 kg/m2 vs. 26.9 ± 4.5 kg/m2 and 37.4 ± 6.4% vs. 26.5 ± 7.4%; p = 0.002 and p < 0.001, respectively). Quality of life was lower in females than in males in the following domains: symptoms (3.8 ± 1.5 vs. 4.6 ± 1.7; p = 0.006); activity limitation (3.6 ± 1.3 vs. 4.4 ± 1.5; p = 0.001); emotional function (3.6 ± 1.9 vs. 4.5 ± 1.7; p = 0.014); and environmental stimuli (3.2 ± 1.6 vs. 4.3 ± 1.9; p = 0.001).
Conclusions:Male asthma patients appear to fare better than do female asthma patients in terms of health-related quality of life, asthma control, BMI, percentage of body fat, and comorbidities.
上一篇：
3年随访观察重症哮喘病情恶化的预测因子
下一篇：
丁酸调控2型固有淋巴细胞依赖的气道高反应性
