在中国，手机短信干预戒烟的疗效研究（“快乐戒烟”）
2016/10/09
摘要
背景：考虑到在中国的戒烟服务的极度匮乏，和在其他国家手机短信干预戒烟的可接受性、可行性和效果，我们提出“在中国，手机短信干预戒烟的疗效研究（“快乐戒烟”）”。该项目的主要目的是评估一个广泛被用于戒烟的手机短信的程序（“快乐戒烟”）是否对中国烟民有效。基于前人的研究戒烟的效果，我们假设“快乐戒烟”在中国将是一个有效的、可行的和负担得起的戒烟计划。
方法/设计：在这个单盲、随机、在中国进行的试验中，约2000个有戒烟愿望的吸烟者将被随机分配，使用一个独立的电话随机系统，包括一个最小化算法平衡性别（男，女），年龄（19-34或> 34岁）、教育水平（≤或>12年），以及尼古丁成瘾的Fagerstrom评分（≤5，>5），“快乐戒烟”，包括激励信息和行为变化的支持，或对照组接收的短信与戒烟无关。短信将被开发得适合中国人。将在干预前进行一项试验性研究，以修改信息和干预措施的库。主要结果将是自我报告的持续吸烟禁欲。次要的结果将是表明某一时间点的禁欲程度。禁欲将在六个时间点（干预后4，8，12，16，20和24周）进行评估。第3个结果是每天吸烟数量的减少。
讨论/提示:本研究结果将为缩小在戒烟干预和预防烟草使用的需求与服务之间的差距提供有价值的见解。它也将作为扩展其他干预的公共卫生意义的移动医疗模式，如心理健康干预。
（苏欣 审校）
BMC Public Health. 2016 Aug 19;16(1):833. doi: 10.1186/s12889-016-3528-5.
The efficacy of mobile phone-based text message interventions ('Happy Quit') for smoking cessation in China.
Liao Y1,2, Wu Q3, Tang J3,4, Zhang F3, Wang X3, Qi C3, He H3, Long J3, Kelly BC5, Cohen J6.
Author information
Abstract
BACKGROUND:Considering the extreme shortage of smoking cessation services in China, and the acceptability, feasibility and efficacy of mobile phone-based text message interventions for quitting smoking in other countries, here we propose a study of "the efficacy of mobile phone-based text message interventions ('Happy Quit') for smoking cessation in China". The primary objective of this proposed project is to assess whether a program of widely accessed mobile phone-based text message interventions ('Happy Quit') will be effective at helping people in China who smoke, to quit. Based on the efficacy of previous studies in smoking cessation, we hypothesize that 'Happy Quit' will be an effective, feasible and affordable smoking cessation program in China.
METHODS/DESIGN:In this single-blind, randomized trial, undertaken in China, about 2000 smokers willing to make a quit attempt will be randomly allocated, using an independent telephone randomization system that includes a minimization algorithm balancing for sex (male, female), age (19-34 or >34 years), educational level (≤ or >12 years), and Fagerstrom score for nicotine addiction (≤5, >5), to 'Happy Quit', comprising motivational messages and behavioral-change support, or to a control group that receives text messages unrelated to quitting. Messages will be developed to be suitable for Chinese. A pilot study will be conducted before the intervention to modify the library of messages and interventions. The primary outcome will be self-reported continuous smoking abstinence. A secondary outcome will be point prevalence of abstinence. Abstinence will be assessed at six time points (4, 8, 12, 16, 20 and 24 weeks post-intervention). A third outcome will be reductions in number of cigarettes smoked per day.
DISCUSSION/IMPLICATIONS:The results will provide valuable insights into bridging the gap between need and services received for smokingcessation interventions and tobacco use prevention in China. It will also serve as mHealth model for extending the public health significance of other interventions, such as mental health interventions.
TRIAL REGISTRATION:NCT02693626 (Registration data April 11, 2016).
KEYWORDS:China; Interventions; Mobile phone-based text message; Smoking cessation; ‘Happy Quit’
BMC Public Health. 2016 Aug 19;16(1):833. doi: 10.1186/s12889-016-3528-5.
