哮喘患者并发症对生产力损失的影响
2016/10/09
摘要
背景：在工作年龄的哮喘患者中，健康相关的生产力损失是一个重要的但被忽视的经济负担的组成部分。我们旨在评估并发症对成人哮喘患者的生产力损失的影响。
方法：在一个成年哮喘雇员的随机样本采中，我们使用一个有效的自我管理疾病问卷（SCQ）测量并发症，以及生产力损失，包括使用验证工具考勤。在2010年，用加拿大元测定生产力损失（$）。我们通过控制潜在的混杂变量，用两个回归模型来评估并发症水平对生产力损失调整后的差异。
结果：284名平均年龄为47.8岁（SD11.8）的成年人被招募（68%为妇女）。平均SCQ评分为2.47（SD 2.97，范围为0-15），平均生产力损失为317.5加元每星期（SD 858.8加元）。SCQ评分每增加一个单位与14%（95% CI 1.02-1.28）生产力损失的可能性增加相关，和9.0%（95% CI 1.01-1.18）生产力损失增加相关。一个SCQ 15分的人比一个SCQ 零分的人几乎每周多损失1000加元的生产力
结论：我们的研究通过阐述工作中的哮喘病人的并发症大大降低了病人的生产力，深化了哮喘经济负担的证据。哮喘管理策略在评估疾病管理策略的效益估算时，必须认识到并发症的作用，适当考虑并发症的影响和生产力损失。
关键词：旷工；哮喘；并发症；出勤；生产力损失
（杨冬 审校）
Respir Res. 2016 Aug 26;17(1):106. doi: 10.1186/s12931-016-0421-9.
The impact of comorbidities on productivity loss in asthma patients.
Ehteshami-Afshar S1, FitzGerald JM2,3,4,5, Carlsten C6,7,8, Tavakoli H9, Rousseau R6, Tan WC10, Rolf JD11, Sadatsafavi M6,7,9.
Author information
Abstract
BACKGROUND:Health-related productivity loss is an important, yet overlooked, component of the economic burden of disease in asthma patients of a working age. We aimed at evaluating the effect of comorbidities on productivity loss among adult asthma patients.
METHODS:In a random sample of employed adults with asthma, we measured comorbidities using a validated self-administered comorbidity questionnaire (SCQ), as well as productivity loss, including absenteeism and presenteeism, using validated instruments. Productivity loss was measured in 2010 Canadian dollars ($). We used a two-part regression model to estimate the adjusted difference of productivity loss across levels of comorbidity, controlling for potential confounding variables.
RESULTS:284 adults with the mean age of 47.8 (SD 11.8) were included (68 % women). The mean SCQ score was 2.47 (SD 2.97, range 0-15) and the average productivity loss was $317.5 per week (SD $858.8). One-unit increase in the SCQ score was associated with 14 % (95 % CI 1.02-1.28) increase in the odds of reporting productivity loss, and 9.0 % (95 % CI 1.01-1.18) increase in productivity loss among those reported any loss of productivity. A person with a SCQ score of 15 had almost $1000 per week more productivity loss than a patient with a SCQ of zero.
CONCLUSIONS:Our study deepens the evidence-base on the burden of asthma, by demonstrating that comorbidities substantially decrease productivity in working asthma patients. Asthma management strategies must be cognizant of the role of comorbidities to properly incorporate the effect of comorbidity and productivity loss in estimating the benefit of disease management strategies.
KEYWORDS:Absenteeism; Asthma; Comorbidities; Presenteeism; Productivity loss
Respir Res. 2016 Aug 26;17(1):106. doi: 10.1186/s12931-016-0421-9.
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