慢性鼻窦炎与勃起功能障碍：一项基于人群的研究
2016/10/09
摘要
很少有研究考察慢性鼻窦炎（CRS）和勃起功能障碍（ED）之间的关系。本研究旨在探讨在一个大的国家样本中慢性鼻窦炎CRS和 勃起功能障碍（ED）之间的关系。分析台湾全民健康保险研究资料库，我们确定了30岁或30岁以上的、在 1996和2007岁之间诊断为慢性鼻窦炎的人群。与性别和年龄匹配的对照组进行比较。我们确定了14039个病例，并招募140387例作为匹配的对照组。两组在同一个数据库进行随访，直到2007年底为作为性功能障碍（ED）的实例。在那些患有慢性鼻窦炎的患者中，有294例（2.1%）在平均随访的3.20（2.33）年里发展成为性功能障碍（ED），然而，对照组平均随访的2.97（2.39）年里，有1661例（1.2%）发展成为性功能障碍。Cox回归分析对性别、年龄、保险费、住宅、高血压、高脂血症、糖尿病、肥胖、冠心病、慢性肾脏病、慢性阻塞性肺疾病、哮喘、过敏性鼻炎、心律失常、缺血性卒中、脑出血，和药物治疗等进行校正。慢性鼻窦炎CRS被发现是在充分调整模型后的性功能障碍ED的独立预测因子（HR，1.51；95% CI = 1.33-1.73；P＜0.0001）。
（杨冬 审校）
Sci Rep. 2016 Aug 31;6:32195. doi: 10.1038/srep32195.
Chronic Rhinosinusitis Associated with Erectile Dysfunction: A Population-Based Study.
Tai SY1,2,3,4, Wang LF5,6,7, Tai CF5,6,8, Huang YT9, Chien CY5,6,8.
Author information
Abstract
Few studies have investigated the relationship between chronic rhinosinusitis (CRS) and erectile dysfunction (ED). This case-control study aimed to investigate the association between CRS and the risk of ED in a large national sample. Tapping Taiwan's National Health Insurance Research Database, we identified people 30 years or older with a new primary diagnosis of CRS between 1996 and 2007. The cases were compared with sex- and age-matched controls. We identified 14 039 cases and recruited 140 387 matched controls. Both groups were followed up in the same database until the end of 2007 for instances of ED. Of those with CRS, 294 (2.1%) developed ED during a mean (SD) follow-up of 3.20 (2.33) years, while 1 661 (1.2%) of the matched controls developed ED, mean follow up 2.97 (2.39) years. Cox regression analyses were performed adjusting for sex, age, insurance premium, residence, hypertension, hyperlipidemia, diabetes, obesity, coronary heart disease, chronic kidney disease, chronic obstructive pulmonary disease, asthma, allergic rhinitis, arrhythmia, ischemic stroke, intracerebral hemorrhage, and medications. CRS was revealed to be an independent predictor of ED in the fully adjusted model (HR = 1.51; 95% CI = 1.33-1.73; P < 0.0001).
Sci Rep. 2016 Aug 31;6:32195. doi: 10.1038/srep32195.
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在中年罹患哮喘极大促进吸烟发展成慢性支气管炎：一项前瞻性的以人群为基础的研究
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食品和吸入性变应原致敏在成人嗜酸性粒细胞性食管炎中的作用
