摘要
目的:尽管研究多年,我们对咳嗽生理的认识仍不全面。对想咳嗽的感觉知之更少。鉴于在普通感冒的过程中,关于想咳嗽的感觉和咳嗽特征的可用临床数据有限,因此,我们试图获得一些关于这些症状的认知和经验。
方法:美国进行了一项由51个问题组成的网上调查。符合条件的调查对象包括18岁及以上的男性和女性,他们在调查前的三个月内患有感冒和咳嗽。那些被证实患有复发性咳嗽、哮喘、慢性支气管炎、慢性阻塞性肺疾病、囊性纤维化、或胃肠道返流的参与者被排除在外。
结果:最初的19530名受访者中,8011名在过去的三个月里患了感冒。其中,6484名(81%)有咳嗽症状;2708名受访者因其咳嗽是由感冒引起而且不具备排除条件组成了分析样本。大多数受访者(62%)汇报在感冒症状发生后一到两天出现咳嗽,45%的受访者认为咳嗽加重了其它的感冒症状。69%的受访者认为相比于其他感冒症状,咳嗽持续的时间更长。有98%的受访者报告说他们想咳嗽,其中,64%将其称之为不可控,65%将其严重程度定为中度。超过一半的受访者(57%)认为想咳的感觉和咳嗽的行为同样令人困扰。虽然想咳嗽和无法控制的咳嗽都是感冒引起的咳嗽里面最麻烦的方面,仍然只有少数(<20%)受访者要求医疗服务人员提供治疗建议。
结论:想咳嗽的感觉和咳嗽的症状是常见的,对感冒患者有显著的影响。了解这些症状的特征可能对有效的管理和新治疗策略的发展有帮助。
(苏欣 审校)
Postgrad Med. 2016 Jun;128(5):485-91. doi: 10.1080/00325481.2016.1185376. Epub 2016 May 21.
Characterization of urge to cough and cough symptoms associated with the common cold: results of a US internet survey.
Eccles R1, Dicpinigaitis P2, Turner RB3, Druce HM4, Adeleke M5, Mann AL6.
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Abstract
OBJECTIVES:Our knowledge of cough physiology is limited despite years of study. Even less is known about the sensation of urge to cough. Given that limited clinical data are available about urge to cough and cough attributes during a common cold, we sought to gain insights into experiences and perceptions related to these symptoms.
METHODS:An internet survey consisting of 51 questions was fielded in the United States. Eligible survey participants included men and women aged 18 years and older who had suffered from a cold with cough within the three months preceding the survey. Participants who confirmed suffering from recurrent cough, asthma, chronic bronchitis, chronic obstructive pulmonary disease, cystic fibrosis, or gastrointestinal reflux were excluded.
RESULTS:Of 19,530 initial respondents, 8011 had a cold in the past three months. Of these, 6484 (81%) had experienced cough symptoms; 2708 respondents with cough due to cold and no exclusionary condition made up the analysis sample. Most respondents (62%) reported thatcough developed one to two days after the onset of cold symptoms, and 45% felt that cough worsened their other cold symptoms. In 69% of respondents, cough outlasted other cold symptoms. Urge to cough was reported by 98% of respondents, and among these respondents, 64% described it as uncontrollable and 65% rated severity as moderate. More than half of respondents (57%) considered the sensation of urge to coughand the act of coughing as equally bothersome. Although urge to cough and inability to control cough were the most bothersome aspects of coughdue to cold, few (<20%) respondents asked healthcare providers for treatment recommendations.
CONCLUSION:Symptoms of urge to cough and cough are common and have a significant impact on cold sufferers. Understanding attributes of these symptoms may provide insights for effective management and the development of novel treatment strategies.
KEYWORDS:Cough; common cold; epidemiology; surveys; symptoms; upper respiratory tract infection; urge to cough
Postgrad Med. 2016 Jun;128(5):485-91. doi: 10.1080/00325481.2016.1185376. Epub 2016 May 21.