传统草药hangekobokuto（半夏厚朴汤）对呼吸道疾病患者喉咙哽塞感的影响
2016/05/31
摘要
喉咙哽塞感（SLT）不是一个少见的症状。SLT的病因是多因素的，心理特征、压力和精神紊乱的压力可能是SLT的重要影响因素。
Hangekobokuto（半夏厚朴汤）是一种对SLT有效的已知的传统草药。本研究对一个短期的hangekobokuto治疗的疗效进行评估。为了评估一个两星期的hangekobokuto处方治疗是否能改善呼吸系统疾病患者的SLT，在2013年4月和2015年8月间进行了回顾性分析。研究期间，共有43例病人是使用了hangekobokuto进行治疗。其中12例（27.9%）患者体验到完全有效的治疗（SLT完全消失），和14例（32.6%）经历了中度有效的治疗（25-99% SLT消失）。支气管哮喘患者和那些没有呼吸系统疾病史的患者对hangekobokuto具有良好的反应。在多元回归分析中，没有发现hangekobokuto对SLT效应的具体的预测因子。因此，目前的研究结果表明，hangekobokuto可能是未控制SLT的一个选择。
（杨冬 审校）
Biomed Rep. 2016 Mar;4(3):384-386. Epub 2016 Feb 5.
Effect of a traditional herbal medicine, hangekobokuto, on the sensation of a lump in the throat in patients with respiratory diseases.
Kagohashi K1, Tamura T1, Ohara G1, Satoh H1.
Author information
Abstract
The sensation of a lump in the throat (SLT) is not a rarely encountered symptom. The etiology of SLT appears to be multifactorial, and the psychological characteristics, stress and pressure of a psychiatric disorder may be significant factors in SLT. Hangekobokuto, one of the traditional herbal medicines, is a known drug that has an effect on SLT. The efficacy of a short-term hangekobokuto treatment on SLT was evaluated. To assess whether a 2-week prescription of hangekobokuto improves SLT mainly in patients with respiratory diseases, a retrospective study was performed between April 2013 and August 2015. During the study period, a total of 43 patients were treated with hangekobokuto. Twelve (27.9%) of the 43 patients were reported to experience completely effective treatment (SLT completely disappeared), and 14 (32.6%) experienced moderately effective treatment (25-99% SLT disappeared). Patients with bronchial asthma and those without a medical history of respiratory disease exhibited a good response to hangekobokuto. No specific predictive factor of the response to hangekobokuto on SLT was identified in the multivariate regression analysis. Therefore, the present results suggested that hangekobokuto could be one of the treatment choices for uncontrolled SLT.
KEYWORDS:Japanese herbal medicine; hangekobokuto; sensation of a lump in the throat
Biomed Rep. 2016 Mar;4(3):384-386. Epub 2016 Feb 5.
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