哮喘联盟

   摘要
   介绍：哮喘是一种可以影响生存质量（QoL）的高发疾病。本研究的目的是探索哮喘患者的QoL以及其与基层医疗中心不同因素之间的关系。
   材料和方法：在城市的医疗中心开展了一项描述性的横断面研究。该研究纳入了共243例17至70岁之间的，病历上有哮喘诊断的患者。患者的QoL使用Mini-Asthma Quality of Life问卷的西班牙版本进行测量，该问卷使用年龄、性别、吸烟、焦虑、抑郁、哮喘的严重程度以及控制情况作为相关的变量。
   结果：入组患者的平均年龄为44.5岁而且71.2%为女性。一半以上的患者(54.3%)患有间歇性哮喘，而45.7%的患者患有持续性哮喘。在Mini-Asthma Quality of Life问卷中的总体评分为7分得到了5.4分。分数的分布为：症状5.4；活动受限5.8；情感功能5.7以及环境刺激4.7。在多变量分析中QoL评分更低但仍然具有统计学显著性(P<.05)的变量是哮喘控制较差（在所有的维度）、抑郁病史（除了环境刺激以外的所有维度），低于2级的教育程度（症状和情感功能）以及患者在过去3年入院史（症状）和使用长效β受体兴奋剂（情感功能）。
   结论：患有间歇性、轻到中度哮喘的患者有较好的QoL。哮喘控制差和有抑郁病史会对患者的QoL产生负面影响。

 

（杨冬 审校）
Semergen. 2016 Feb 5.pii:S1138-3593(15)00441-4.doi:10.1016/j.semerg.2015.12.014. [Epub ahead of print]



 

Quality of life and associated factors in asthma in a Primary Care Center. Application of the reduced version of theAsthma Quality of Life Questionnaire.
 

[Article in Spanish]
Flor-Escriche X1, Méndez-Gómez J2, Poblet-Cortés R1, Lamarca-Fornell L1, Álvarez-Álvarez S1, Davies-Daunas SA1.
 

Abstract
INTRODUCTION:Asthma is a highly prevalent disease that can affect the quality of life (QoL). The objective of this study is to determine the QoL in patients with asthma and its relationship with different factors in a Primary Care centre.
MATERIAL AND METHODS:A descriptive, cross-sectional study was conducted in an urban health centre. The study included a total of 243 patients between 17 to 70 years who had a diagnosis of asthma in their medical records. The QoL was measured using the Spanish version of the Mini-Asthma Quality of Life Questionnaire, with age, sex, smoking, anxiety, depression, severity and control of asthma as associated variables.
RESULTS:The mean age was 44.5 years and 71.2% were women. More than half (54.3%) had intermittent asthma, and 45.7% persistent asthma. The overall score in the Mini-Asthma Quality of Life Questionnaire was 5.4 out of 7. The scores by dimensions were: symptoms 5.4; limitation of activities 5.8; emotional function 5.7, and environmental stimuli 4.7. The variables with a worse QoL score that remained statistically significant (P<.05) in the multivariate analysis were poor control of asthma (in all dimensions), history of depression (in all except environmental stimuli), educated to less than secondary level (symptoms and emotional function), and patients admitted to hospital in the past 3 years (symptoms) and who used long-term beta-adrenergics (emotional function).
CONCLUSIONS:Patients with intermittent, mild and moderate asthma have a good QoL. Poor control of the asthma and a history of depression negatively affect the QoL.
 

Semergen. 2016 Feb 5.pii:S1138-3593(15)00441-4.doi:10.1016/j.semerg.2015.12.014. [Epub ahead of print]