哮喘联盟

   摘要
   背景：在过去二十年间，肥胖儿童与青少年的数量已经翻了一倍多。根据儿童期肥胖增长的这一趋势，超重哮喘儿童的数量将有惊人的增加。
   目的：本研究通过描述性对比调查分析，旨在探索肥胖与超重哮喘儿童和正常体重哮喘儿童在生活质量(QOL)、健康状况方面的差异。
   方法：本对比研究包括了90例9-14岁超重和正常体重的哮喘儿童。健康状况评价包括哮喘相关的缺课天数、急诊就诊(ED)次数、住院次数、白天喘息次数、夜间憋醒次数。生活质量则运用儿科哮喘生活质量调查问卷(PAQLQ)来评价。
   结果：与正常体重组相比，在急诊就诊次数、住院次数、白天喘息次数方面，肥胖组的比例最高。危险度比(RR)分析显示，肥胖组急诊就诊风险比超重和正常体重组高2.73 (95% CI: 2.15 - 3.63)倍，住院风险则高2.46 (95% CI: 1.97 - 3.19)倍。哮喘严重程度是整体生活质量的重要预测因素(β = -23.737, p = 0.002)。
   结论：本研究表明，肥胖者罹患重度哮喘的风险更高，这一发现与其他研究结果一致，进一步支持了肥胖是预防哮喘和改善哮喘症状的潜在可变危险因素。

 

（杨冬 审校）
JPediatrHealthCare. 2016Feb11.pii:S0891-5245(16)00009-2.doi:10.1016/j.pedhc.2016.01.005. [Epub ahead of print]


 

Quality of Life and Health Outcomes in Overweight and Non-Overweight Children With Asthma.
 

Manion AB, Velsor-Friedrich B.

Abstract
BACKGROUND:During the past two decades, the number of children and adolescents who are obese has more than doubled. Following this trend in childhood obesity, there has been an alarming increase in the number of children with asthma who are overweight.
OBJECTIVE:The aim of this study was to examine the differences in quality of life (QOL) and health outcomes of obese and overweight children withasthma compared with normal-weight children with asthma using a descriptive comparative survey design.
METHODS:This comparative study consisted of 90 overweight and normal-weight 9- to 14-year-olds with asthma. Health outcomes examined included asthma-related missed number of school days, emergency department (ED) visits, hospitalizations, number of days wheezing, and number of night awakenings. QOL was measured using the Pediatric Asthma Quality of Life Questionnaire.
RESULTS:The obese group reported the highest percentage of ED visits, hospitalizations, and number of days wheezing compared with the normal-weight group. A risk ratio analysis showed that the obese group had an overall 2.73 (95% confidence interval [CI] 2.15, 3.63) times higher likelihood of going to the ED and a 2.46 (95% CI 1.97, 3.19) times higher likelihood of hospitalization than the overweight and normal-weight groups. Asthmaseverity was a significant predictor of overall QOL (β = -23.737, p = .002).
CONCLUSIONS:The study results are consistent with other investigations that demonstrate that obese persons are at higher risk of experiencing severe asthma symptoms and support obesity as a potentially modifiable risk factor for asthma mitigation and prevention.
 

JPediatrHealthCare. 2016Feb11.pii:S0891-5245(16)00009-2.doi:10.1016/j.pedhc.2016.01.005. [Epub ahead of print]