哮喘联盟

   摘要
   背景：社会因素和家庭因素会影响儿童哮喘控制的概率。父母的生活质量作为哮喘儿童疾病控制的概率的相关预测因子，一直以来都未被充分探讨。
   目的：判断父母的生活质量是否可以预测儿童中期哮喘的控制。
   方法：对4至14岁患有活动性哮喘的儿童进行纵向研究。父母的生活质量利用特定的ifabi-r量表进行评价，得分越高表示生活质量越差。16周后，对儿童哮喘控制情况与父母的生活质量的关系，使用多变量法进行了分析，并对疾病、儿童和家庭因素的影响进行了校正。
   结果：对452名儿童的数据进行了分析（中位年龄9.6岁，63.3%为男性）。父母的生活质量可以预测哮喘的控制；在第二次的回访中，对哮喘有良好控制的从初始ifabi-r评分上每增加1分则比值比会调整0.56（95%置信区间，0.37-0.86），哮喘急性发作的为2.58（95%置信区间，1.62-4.12），计划外访视的为2.12 (95%可信限1.33-3.38)，急诊就诊的为2.46 (95%置信区间，1.18-5.13)。ifabi-r量表的最高四分位数对于预测哮喘控制不良，有34.5%的敏感性和82.2%特异性。
   结论：父母的生活质量越差，儿童中期哮喘控制越差。评估父母的生活质量有助于疾病的管理决策。
 

（杨冬 审校）
PediatrPulmonol. 2015 Nov 24.doi: 10.1002/ppul.23336. [Epub ahead of print]

 

Looking beyond patients: Can parents' quality of life predict asthma control in children?
 

Cano-Garcinuño A1, Mora-Gandarillas I2, Bercedo-Sanz A3, Callén-Blecua MT4, Castillo-Laita JA5, Casares-Alonso I6, Forns-Serrallonga D7, Tauler-Toro E8, Alonso-Bernardo LM9, García-Merino Á10, Moneo-Hernández I11, Cortés-Rico O12, Carvajal-Urueña I9, Morell-Bernabé JJ13, Martín-Ibáñez I14,Rodríguez-Fernández-Oliva CR15, Asensi-Monzó MT16, Fernández-Carazo C17, Murcia-García J18, Durán-Iglesias C19, Montón-Álvarez JL20,Domínguez-Aurrecoechea B21, Praena-Crespo M22.
 

Abstract
BACKGROUND:Social and family factors may influence the probability of achieving asthma control in children. Parents' quality of life has been insufficiently explored as a predictive factor linked to the probability of achieving disease control in asthmatic children.
OBJECTIVE:Determine whether the parents' quality of life predicts medium-term asthma control in children.
METHODS:Longitudinal study of children between 4 and 14 years of age, with active asthma. The parents' quality of life was evaluated using the specific IFABI-R instrument, in which scores were higher for poorer quality of life. Its association with asthma control measures in the child 16 weeks later was analyzed using multivariate methods, adjusting the effect for disease, child and family factors.
RESULTS:The data from 452 children were analyzed (median age 9.6 years, 63.3% males). The parents' quality of life was predictive for asthma control; each point increase on the initial IFABI-R score was associated with an adjusted odds ratio (95% confidence interval) of 0.56 (0.37-0.86) for good control of asthma on the second visit, 2.58 (1.62-4.12) for asthma exacerbation, 2.12 (1.33-3.38) for an unscheduled visit to the doctor, and 2.46 (1.18-5.13) for going to the emergency room. The highest quartile for the IFABI-R score had a sensitivity of 34.5% and a specificity of 82.2% to predict poorly controlled asthma.
CONCLUSIONS:Parents' poorer quality of life is related to poor, medium-term asthma control in children. Assessing the parents' quality of life could aid disease management decisions.
 

PediatrPulmonol. 2015 Nov 24.doi: 10.1002/ppul.23336. [Epub ahead of print]