哮喘联盟

   摘要
   背景：我们开发了一种演算方法以评估记录的咳嗽片段，并将它们与相似的非咳嗽的声音区分。
   目的：为了测量健康青年人的咳嗽片段，对吸烟者和非吸烟者录音超过24小时，期间保持正常活动。
   设计：研究对象为学生，年龄20-40岁。采用一个便携式录音机进行24小时的录音。数据分析采用在本研究中开发和测试的演算方法进行分析。
   结果：选用70名学生。录音记录了1704 个小时，共2628咳嗽片段 。咳嗽演算方法成功地检测到88.5%的咳嗽录音片段和95.6%的非咳嗽片段。有一个明显的趋势即吸烟者咳嗽明显增多。秋季是咳嗽高发季节，平均每天咳嗽发作（58.65），而夏季是咳嗽低发季节，平均最低（14.19）。自诉的咳嗽和录音咳嗽之间存在明显的关联。中午至午夜期间咳嗽发作明显更加频繁。（P < 0.0001  ）。
   结论：健康的青年人日常咳嗽范围较大。睡眠时间咳嗽发作明显减少。相对于夏季和冬季而言，秋季和春季咳嗽发作明显增多，影响仅次于环境因素。吸烟者咳嗽发作比率较高。如果咳嗽监测仪能够区分咳嗽变异（即健康与病人的咳嗽变异），且其灵敏度和特异性能得到严格的验证，则该仪器的检测数据将很有价值，可以使得用药或选择其他改善症状的决策变得容易。

 

（苏欣 审校）
J Asthma. 2015 Oct 29:1-6. [Epub ahead of print]


 

Diurnal and seasonal variation of cough episodes in healthy young adults.
 

Zigel Y1, Goldbart A2,3, Freud T2,4, Erew A1, Abu Leil M1, Tocker Y1, Levi I1, Urkin J2,3,4.
 

Abstract
SETTING:We developed an algorithm to assess recorded cough episodes and differentiate them from similar, non-cough sounds.
OBJECTIVE:To measure cough episodes in healthy young adults, cigarette smokers and non-smokers over a 24-hour recording period, during the course of normal activity.
DESIGN:The study subjects were students, aged 20-40 years old. 24-hour sound recordings were conducted by a portable recorder. Analysis used an algorithm that was developed and tested in the study.
RESULTS:Seventy students were recruited. Recordings included 2628 cough episodes in 1704 h of recording. The cough detection algorithm successfully detected 88.5% of recorded cough episodes and 95.6% of non-cough sounds. There was a clear tendency for more coughs among smokers. Autumn was the season with the highest mean cough episodes per day (58.65), while summer had the lowest (14.19). There was a strong correlation between self-reported cough episodes and recorded coughs. Cough episodes were significantly more frequent between noon and midnight (p < 0.0001).
CONCLUSION:There is a very large range in daily coughs among healthy young adults. During sleeping hours there are less cough episodes. In autumn and spring there are more cough episodes compared to summer and winter, probably secondary to environmental factors. In smokers, the coughing rate is relatively high. If thecough detection device will be able to discriminate between cough variants (i.e. healthy versus patient), and stringent validation will confirm sensitivity and specificity, valuable data from this device may ease the decision regarding medications, or any other changes in order to improve outcome.
 

J Asthma. 2015 Oct 29:1-6. [Epub ahead of print]