哮喘联盟

   摘要
   本研究旨在对吸烟女性的尿流动力学进行评估，包括烦人的下尿路症状，以帮助理解吸烟对下尿路功能的潜在影响。
   方法：对1991年1月-2009年12月间英国三级转诊中心接受尿流动力学研究的11678例女性数据进行回顾性分析。所有报告吸烟的女性均纳入研究。根据国际尿控学会的推荐进行尿流动力学检测和结果分析。
   结果：总体来说，共2476例（21.2%）女性报告吸烟。膀胱过度活动症状（OAB）在吸烟者更常见(比值比 1.14, p = 0.006)。女性吸烟者明显抱怨遗尿(比值比 2.26, p < 0.001)和性交尿失禁（CI；比值比 1.14, p < 0.001)。逼尿肌过度活动(DO; 比值比 1.42, p < 0.001)和逼尿肌过度活跃失禁(DOI; 比值比 1.42, p < 0.001)是最主要的尿量动力学改变。吸烟与SUI (比值比1.08, p = 0.213)或尿动态应力性尿失禁(比值比 0.86, p = 0.001)不显著相关。
   结论：吸烟与OAB、遗尿和CI相关。DO和DOI是主要的尿流动力学改变。
 

（苏欣 审校）
Urol Int. 2015 Oct 10. [Epub ahead of print]


 

The Functional Effects of Cigarette Smoking in Women on the Lower Urinary Tract.
 

Madhu C1, Enki D, Drake MJ, Hashim H.
 

Abstract
The aim of the study was to evaluate the urodynamic findings in women who smoke cigarettes, with bothersome lower urinary tract symptoms, to help develop an understanding of potential impact of smoking on the lower urinary tract function.
METHODS:A database of 11,678 women who underwent urodynamic testing in a tertiary referral centre in the United Kingdom, from January 1991 to December 2009 was retrospectively analysed. All women reporting cigarette smoking were included in the study group. Urodynamic testing and interpretation of results were done in accordance with the recommendations of the International Continence Society.
RESULTS:Overall, 2,476 (21.2%) women reported smoking cigarettes. Overactive bladder symptoms (OAB) were more common in smokers (OR 1.14, p = 0.006). Female smokers significantly complained of secondary nocturnal enuresis (OR 2.26, p < 0.001) and coital incontinence (CI; OR 1.14, p < 0.001). Detrusor overactivity (DO; OR 1.42, p < 0.001) and detrusor overactivity incontinence (DOI; OR 1.42, p < 0.001) were the most significant urodynamic findings. Smoking was not shown to be significantly associated with SUI (OR 1.08, p = 0.213) or urodynamic stress incontinence (OR 0.86, p = 0.001).
CONCLUSION:Cigarette smoking is associated with OAB, secondary nocturnal enuresis and CI. DO and DOI are the most significant urodynamic findings.
 

Urol Int. 2015 Oct 10. [Epub ahead of print]