哮喘联盟

   摘要
   本研究的目的是提高合理用药的意识。数据源于卫生部物质资源管理系统。使用了全球哮喘防治创议、慢性阻塞性肺疾病全球倡议和合理用药指南，以便进行恰当治疗。我们也调查了是否进行任何一种降阶方法或体育锻炼。使用描述性统计来进行统计分析，以确定平均值，标准偏差和频数。结果表明医疗服务提供者忽视了潜在药物反应或不良相互作用，这反映出他们对目前的治疗指南缺乏依从性，存在35.8%的不合理用药。因此，应该使用降阶方法以降低费用或缩窄抗菌谱，抗生素的选择应该考虑到耐药性，应该分析培养方法，在联合用药前应优选单药治疗。
 

（苏欣 审校）
JInfectPublicHealth. 2015Jul9.pii:S1876-0341(15)00127-6.doi:10.1016/j.jiph.2015.06.002. [Epub ahead of print]
 

Are treatment guides and rational drug use policies adequately exploited in combating respiratory system diseases?
 

Dogan M1, Mutlu LC2, Yilmaz İ3, Bilir B4, Varol Saracoglu G5, Yildirim Guzelant A6.
 

Abstract
The aim of the present study was to increase awareness regarding the rational use of medicines. The data were obtained via the Material Resources Management System Module of the Ministry of Health. For the appropriateness of treatments, the Global Initiative for Asthma, the Global Initiative for Chronic Obstructive Lung Disease, and the guidelines for the rational use of medicines were used. We also investigated whether any de-escalation method or physical exercise was performed. Statistical analyses were performed using descriptive statistics to determine the mean, standard deviation, and frequency. The results showed that healthcare providers ignored potential drug reactions or adverse interactions, and reflecting the lack of adherence to the current treatment guides, 35.8% irrational use of medicines was recorded. Thus, de-escalation methods should be used to decrease costs or narrow the antibiotic spectrum, antibiotic selection should consider the resistance patterns, culturing methods should be analyzed, and monotherapy should be preferred over combination treatments.
 

JInfectPublicHealth. 2015Jul9.pii:S1876-0341(15)00127-6.doi:10.1016/j.jiph.2015.06.002. [Epub ahead of print]