哮喘联盟

   摘要
   上气道咳嗽综合征（UACS），以前被称为鼻后滴漏综合征，是慢性咳嗽的最常见的病因之一。然而，UACS/鼻后滴漏综合征的发病机制尚不清楚，而且世界上各个国家的医生对这种疾病有不同的定义和治疗方法。UACS的各种拟议发病机制包括早期的鼻涕滴漏理论，随后的慢性气道炎症理论，还有近期的感觉神经过敏理论。此外，一些研究人员认为，UACS是咳嗽过敏综合征的临床表型。然而，世界各地治疗UACS的一般原则是相似的，治疗的具体细节不同。本文综述UACS的各种定义、致病机理、治疗及其他方面，以帮助临床医生提高诊断和治疗这种综合征的认识。
 

（苏欣 审校）
Kaohsiung J Med Sci. 2015 May;31(5):223-228. doi: 10.1016/j.kjms.2015.01.005. Epub 2015 Mar 4.
 

Advances in upper airway cough syndrome.
 

Yu L1, Xu X1, Lv H1, Qiu Z2.
 

Abstract
Upper airway cough syndrome (UACS), previously referred to as postnasal drip syndrome, is one of the most common causes of chronic cough. However, the pathogenesis of UACS/postnasal drip syndrome remains unclear, and physicians in countries throughout the world have different definitions and ways of treating this disease. The various proposed pathogeneses of UACS include the early postnasal drip theory, subsequent chronic airway inflammation theory, and a recent sensory neural hypersensitivity theory. Additionally, some researchers suggest that UACS is a clinical phenotype of cough hypersensitivity syndrome. While the general principles involved in treating UACS are similar throughout the world, the specific details of treatment differ. This review summarizes the various definitions, pathogenic mechanisms, treatments, and other aspects of UACS, to aid clinicians in expanding their knowledge of how to diagnose and treat this syndrome.
 

Kaohsiung J Med Sci. 2015 May;31(5):223-228. doi: 10.1016/j.kjms.2015.01.005. Epub 2015 Mar 4.